Charcot Fund: fundamental research

The gut-(microbiota-)brain axis in multiple sclerosis: unravelling the involvement of the CNS barriers.

Although you might not expect it, gut bacteria can affect how our brains work. An increasing amount of research is showing that these gut bacteria also play a role in various diseases of the nervous system, including multiple sclerosis. One major factor in the protection of our brains is the blood-brain barrier, which prevents unwanted substances from entering the nervous system. In this project, we shall be investigating whether and how gut bacteria can affect the blood-brain barrier in MS patients.

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