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Laureates 2012

IL-17, Treg and miRNA regulation in EAE and MS

Dr. Vincent van Pesch – Dr. Karima Jnaoui – Prof. Christian Sindic - Dr Catherine Uyttenhove - Dr Jacques Van Snick
Cliniques Universitaires Saint-Luc / Service de Neurologie - Units of Cellular Genetics and experimental Medicine, Institute of Cellular Pathology / U.C.L.
€43,000
1 year
2 years

The lymphocytes that produce interleukin-17 (IL-17) are involved in the triggering of immune disorders such as multiple sclerosis (MS). This project aims to identify the factors involved in the differentiation of the lymphocyte population and assess their use as potential biomarkers of the activity of the disease. A second aspect of the project will consist of studying the effect of a treatment neutralising IL-17 on an MS mouse experimental model.

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