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The disease symptoms and treatments

Multiple sclerosis (MS) is the most common neurological disorder among young adults and often results in a handicap. It is an auto-immune disease in which the body attacks its own tissues. The immune attack in MS targets the central nervous system. The lesions are well-localised and are called “plaques”.

News

27.04.20

Coronavirus and multiple sclerosis - update

The Belgian Charcot Foundation adheres to the guidelines of our health authorities: https://www.info-coronavirus.be/nl/ or https://www.info-coronavirus.be/fr/, which are updated when necessary.

The Belgian Charcot Foundation follows the advice of the Belgian Study Group for MS regarding the treatment of MS patients.

Therefore, following recommendations apply:

  1.        The preventive measures provided to the general population (https://www.info-coronavirus.be/nl/ or https://www.info-coronavirus.be/fr/) do apply even more to patients with MS, especially when treated with disease modifying drugs.
  2.        In patients with MS treated with disease modifying drugs it is recommended:
  •           Interferon-beta (Avonex®, Betaferon®, Rebif®), glatiramer acetate (Copaxone®), teriflunomide (Aubagio®),dimethyl fumarate (Tecfidera®), fingolimod (Gilenya®), natalizumab (Tysabri®): treatment to be continued
  •           Ocrelizumab (Ocrevus®), cladribine (Mavenclad®), alemtuzumab (Lemtrada®), rituximab (Mabthera®): start or redosing of treatment to be postponed if the disease severity/activity of the patient allows
  1.        Persons with MS who are treated with disease modifying drugs and are infected with Covid-19: to stop the ongoing treatment until recovery
18.03.20

Respect

Today's heroes are not only the care workers, but also the men and women in the shadows in logistics, the post office, garbage collectors, etc., not forgetting the researchers. Their mission is to find ways to solve this crisis, today but also tomorrow.

MS patients are a high-risk group and, like the rest of the population, need to follow the recommendations scrupulously and more.  

The Fondation Charcot Stichting remains available for any questions and will relay them to expert neurologists. Our fund-raising actions are continuing because tomorrow too, research will be essential to find better treatments, faster diagnosis and possible prevention.

 

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Laureates of Charcot Fund 2020

All laureates

Grant

€60,000/ 2 years

Prof. Jerome Hendriks, Dr. Mansour Haidar and Prof. Noam Zelcer

The project

Disturbed lipophagy skews foamy macrophages to a disease-promoting phenotype in progressive MS
UHasselt, Biomedical Research Institute
Detail of the grant

Grant

€45,000/ 2 years

Prof. Veerle Somers and Dr. Judith Fraussen

The project

Validation of age-associated B cells as therapeutic targets in MS
UHasselt, Biomedical Research Institute
Detail of the grant

Grant

€50,000/ 2 years

Prof. Niels Hellings and Prof. Laurent Gillet

The project

Epstein Barr-virus and MS: new tricks from an old dog. Does imprinting of inflammatory monocytes provide an answer?
UHasselt, Biomedical Research Institute and Université de Liège
Detail of the grant

Grant

€60,000/ 2 years

Prof. Vincent van Pesch, Dr. M. Alhouayek, Prof. G. Muccioli and Dr. L. D’auria

The project

Lipids and microRNAs from Extracellular Vesicles in Multiple Sclerosis: deciphering pathophysiology to discover novel therapeutic pathways
UCLouvain
Detail of the grant

Grant

€47,000/ 2 years

Dr. Bieke Broux

The project

Inflammasome activation in T lymphocytes: a new player in the complex immune response in multiple sclerosis patients
UHasselt
Detail of the grant

Grant

€39,235

Prof. Jeroen Van Schependom

The project

Application of transcranial Alternating Current Stimulation to enhance remyelination
Vrije Universiteit Brussel
Detail of the grant

Grant

€51,590

Prof. Tom vanden Berghe

The project

Therapeutic exploration of lead ferroptosis inhibitors in MS
UAntwerpen/UGent
Detail of the grant

Grant

€30,000

Dr. Elisabeth Piccart and Dr. Tim Vanmierlo

The project

Boosting myelin production in human pluripotent stem cell-derived oligodendrocytes
UHasselt
Detail of the grant

Grant

€62,013/ 2 years

Prof. Peter Feys

The project

Implicit and explicit learning strategies for improving mobility-related cognitive motor dual task performance in Multiple Sclerosis
UHasselt
Detail of the grant

Grant

€50,000/ 2 years

Prof. Roosmarijn Vandenbroucke

The project

Deciphering the role of extracellular vesicles (EVs) in multiple sclerosis
UGent
Detail of the grant

Last newsletter

Twice a year, the Charcot Foundation publishes a Bulletin which wants to be the objective reflection of research and last acquisitions in Multiple sclerosis as well in the field of our knowledge of the disease as of the new treatments under study

APRIL 2020