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Dr Barbara Willekens and Prof. Nathalie Cools

Development of a CD19 CAR T cell therapy for multiple sclerosis


€ 72,400 / 2 years

There is a clear unmet need for innovative treatments that can suppress ongoing inflammatory disease activity in treatment refractory relapsing-remitting MS (RRMS) patients. The grant of the Belgian Charcot Foundation enables us to start developing CD19 CAR T cells for the use in MS and related autoimmune diseases that are driven by pathogenic B cells. While the current project is focused on laboratory research, we are committed to paving the road towards a first-in-man clinical trial in the future.